Mixing Cocaine and Xanax

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Mixing cocaine and Xanax can be a dangerous combination, as both drugs are central nervous system depressants. When taken together, they can lead to serious side effects such as respiratory depression, coma, and even death.

Cocaine is an illicit stimulant drug used recreationally for centuries, while Xanax is a prescription medication typically used by physicians to treat anxiety disorders. The two drugs are especially hazardous when combined.

Why? Cocaine and Xanax have vastly different effects on the body. If you take them together, you might experience extreme sedation or agitation, slowed breathing, impaired judgment, and an increased risk of overdose.

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What Are Stimulants & Depressants?

Stimulants are drugs that increase the activity of the central nervous system and can produce feelings of alertness, energy, and euphoria. Cocaine is an example of a stimulant drug that is often abused for its pleasurable effects, but it also has its downsides.

Depressants are drugs that have the opposite effect and reduce the activity of the central nervous system. Xanax is an example of a depressant used to treat anxiety disorders by calming nerves and reducing stress levels. As a prescription drug, you should only take Xanax with physician supervision.

Commons Symptoms of Stimulant Use

When you use stimulants, you may experience a range of symptoms, such as increased alertness and energy, increased confidence, talkativeness, and euphoria. Less pleasant side effects can include restlessness, anxiety, agitation, insomnia, and elevated heart rate. While cocaine is considered a “party” drug because it heightens energy, it can also ruin your fun if you experience negative side effects.

Side Effects of Depressants

Depressants have the opposite effect on the body and can produce feelings of relaxation and drowsiness. Common symptoms include slowed breathing, impaired coordination, confusion, and slurred speech. That is why the dosage of a depressant like Xanax needs to be regulated by a healthcare professional. Take enough, and it will reduce anxiety; take too much, and you could harm yourself.

Additional side effects of Xanax include:

  • Lightheadedness.
  • Depression.
  • Headache.
  • Dry mouth.
  • Constipation.
  • Diarrhea.

How Do Stimulants & Depressants Interact When Mixed?

When you mix stimulants and depressants, you send mixed signals to your central nervous system. The body and the brain may be unable to simultaneously process those messages, causing dangerous side effects.

Mixing cocaine and Xanax can be dangerous as the two drugs have conflicting effects on the body. When taken together, they can lead to serious reactions such as respiratory depression, coma, and even death. The combination of these substances can impair judgment and increase the risk of overdose due to the combined impact on respiration and heart rate.

Why Would Someone Use Cocaine & Xanax Together?

Some people may mix cocaine and Xanax to counteract the negative side effects of each drug. For example, Xanax can be used to reduce the anxiety and agitation caused by cocaine, while cocaine can be used to increase the feeling of euphoria associated with Xanax. However, it’s important to understand that this combination is extremely dangerous and can lead to serious medical complications.

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Side Effects & Dangers of Mixing Xanax & Cocaine

Mixing cocaine and Xanax can lead to serious side effects because these two substances have vastly different influences on the body. The combination can cause:

  • Extreme sedation.
  • Agitation.
  • Impaired judgment.
  • Slowed breathing.
  • Confusion.
  • Coma.

Increased Risks of Addiction & Overdose

Mixing cocaine and Xanax can also increase the risk of addiction to both drugs. Taking the two substances together limits the effectiveness of each. That can lead you to take higher doses of one or both to get the desired effect. Abusing either can also increase the risk of becoming addicted to other drugs.

Taking these drugs together escalates your chance of overdosing due to their combined impact on respiration and heart rate. They hide some of the negative side effects of each other, making it difficult to recognize the warning signs of overdose.

In addition, asking your body to process two toxins simultaneously can overload your system leading to an overdose. Signs of overdose include:

  • Vomiting.
  • Shallow breathing.
  • Loss of consciousness.
  • Chest pain.
  • Seizures.
  • Extreme drowsiness.
  • Slow heart rate.
  • Coma.
  • Paralysis.
  • Death.

If you witness any of these signs or symptoms, it’s vital to call for medical help right away. If they intervene early enough, professionals can often treat overdose, so calling 911 could save a life.

Paramedics and other professionals will use treatments like naloxone, activated charcoal, and breathing support to counteract the effects of the drugs. After treating the emergency symptoms of overdose, many people remain in the hospital for observation.

Amplified Side Effects & Complications

Mixing cocaine and Xanax can lead to amplified side effects, such as slowed breathing and heart rate, impaired coordination, and confusion. This combination can increase the risk of overdose and death.

Treating Polysubstance Abuse Symptoms & Addiction

Using more than one drug at a time (or within a short time frame) is known as polysubstance use and can occur intentionally (you want to experience the effects of cocaine and Xanax together) or unintentionally (someone laces one drug with another without your knowledge). Either way, the practice is dangerous. That’s why it’s important to understand the risks of mixing any two drugs.

If you or someone you know is struggling with substance use disorder, seek professional help immediately! Professional addiction treatment centers, like Guardian Recovery, provide comprehensive care tailored to each individual’s needs. This type of care can help you safely detox from substances, learn healthy coping skills and establish a lifestyle of recovery.

Treatment Options for Cocaine & Xanax Addiction

There are many treatment options available for cocaine and Xanax addiction. Treatment typically involves a variety of counseling, behavioral, and alternative therapies to help address the underlying causes of addiction, as well as medications that keep you comfortable while substances work their way out of your system. Guardian Recovery provides comprehensive treatment for cocaine misuse, whether you are taking it alone or with other substances.

Seek Professional Help for Cocaine & Xanax Abuse

If you or someone you know is abusing cocaine and Xanax, it’s essential to seek professional help right away to avoid serious health complications or death. Treatment options include counseling, cognitive behavioral therapygroup support, and 12-step programs. It’s important to remember that recovery from substance abuse is a long process and best undertaken with the help of trained professionals like those at Guardian Recovery.

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Mixing cocaine and Xanax is extremely dangerous and can cause serious side effects such as extreme sedation or agitation, impaired judgment, slowed breathing, confusion, coma, addiction, and overdose. The combination should not be taken lightly, so if you or someone you know is taking these two drugs together, seek professional help like that offered at Guardian Recovery. We can help you detox from cocaine and other substance and offer practical, multi-phased clinical addiction treatment customized to suit your personal needs. Our team of dedicated professionals will provide support and guidance from the moment you enter our doors. We offer a free, no-obligation health insurance benefit check for men and women who are currently insured through any major regional or national provider. We work closely with most major insurance providers in order to make our treatment services as accessible as possible. Begin your journey of healing by contacting us today.


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Disclaimer: Does not guarantee specific treatment outcomes, as individual results may vary. Our services are not a substitute for professional medical advice or diagnosis; please consult a qualified healthcare provider for such matters.

  1. https://drugabuse.com/online/mixing-cocaine-and-xanax/
  2. https://www.cdc.gov/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309369/

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Reviewed professionally for accuracy by:

Ryan Soave


Ryan Soave brings deep experience as a Licensed Mental Health Counselor, certified trauma therapist, program developer, and research consultant for Huberman Lab at Stanford University Department of Neurobiology. Post-graduation from Wake Forest University, Ryan quickly discovered his acumen for the business world. After almost a decade of successful entrepreneurship and world traveling, he encountered a wave of personal and spiritual challenges; he felt a calling for something more. Ryan returned to school and completed his Master’s Degree in Mental Health Counseling. When he started working with those suffering from addiction and PTSD, he found his passion. He has never looked back.

Written by:

Cayla Clark

Cayla Clark

Cayla Clark grew up in Santa Barbara, CA and graduated from UCLA with a degree in playwriting. Since then she has been writing on addiction recovery and psychology full-time, and has found a home as part of the Guardian Recovery team.

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